Yan Wang (East Tennessee State University)
Sr. Research Investigator, Thomas Jefferson University, Philadelphia, PA · United States
Editorial leadership for Journal of Public Health International ISSN 2641-4538
Research interests
- Neuroinflammation In Central Nervous System (Cns)
- Peripheral Nervous System (Pns) Epigenetic Modifications In T Cells Pathogenic Mechanisms In Autoimmune Diseases Pathogenic Mechanisms
- Signal Transduction Pathways In Ageing-Associated Diseases Stem Cell Dynamics
- Neurogenesis
- Neuronal Regeneration
- Apoptosis
- Autophagy
Biography
Dr. Yan Wang is a Senior Research Investigator at Thomas Jefferson University in Philadelphia, PA, United States, with doctoral training from East Tennessee State University. Her research spans molecular mechanisms underlying neurological and immunological disorders, including investigations of DNA damage responses in neuropsychiatric diseases, noradrenergic system regulation, post-translational modifications in Huntington's disease pathogenesis, and immune regulation in viral infections. Dr. Wang's work on regulatory T cells has made significant contributions to understanding autoimmune disease mechanisms, most notably through her highly cited 2021 publication "AIM2 in regulatory T cells restrains autoimmune diseases," which has been cited 157 times. Her studies have elucidated critical pathways involving Foxp3 expression, microRNA regulation in T regulatory cells, and neurotoxin-induced cellular damage in neuronal models.
Selected publications
- AIM2 in regulatory T cells restrains autoimmune diseases 2021 cited 157×
- Schwann cell–derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment 2018 cited 46×
- Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity 2022 cited 38×
- IL-10 Paradoxically Promotes Autoimmune Neuropathy through S1PR1-Dependent CD4+ T Cell Migration 2018 cited 20×
- Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells 2022 cited 7×
- Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases 2021 cited 2×
Ranked by citation impact (Crossref) where available, newest otherwise · verified via ORCID.
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This journal is guided by Yan Wang (Sr. Research Investigator, Thomas Jefferson University, Philadelphia, PA) and a peer-review board of practising researchers. Open access, author-retained copyright (CC BY), and a clear editorial process.